Related Experiment Video
Updated: Jan 24, 2026
06:54
Dissection of Human Retina and RPE-Choroid for Proteomic Analysis
Published on: November 12, 2017
11.8K
Choroidal binarization analysis: clinical application.
Sara Crisostomo1, Joana Cardigos2, Diogo Hipólito Fernandes2
1Department of Ophthalmology, Central Lisbon Hospital Center, Alameda de Santo António DOS Capuchos, Santo António, 1169-050, Lisbon, Portugal. saralbcrisostomo@gmail.com.
International Ophthalmology
|May 30, 2019
Summary
Binarization of optical coherence tomography images offers a non-invasive method to measure choroidal components. This technique shows promise for detailed study of choroidal subcomponents in various ocular conditions.
Area of Science:
- Ophthalmology
- Medical Imaging
- Biomedical Engineering
Background:
- Optical coherence tomography (OCT) enables non-invasive in vivo assessment of ocular structures.
- Binarization techniques applied to OCT scans allow for the separation and measurement of choroidal components.
Purpose of the Study:
- To systematically review the scientific literature on binarization techniques applied to OCT scans of the choroid.
- To analyze the application, advantages, and disadvantages of choroidal binarization in various ocular diseases and conditions.
Main Methods:
- Systematic literature search of the PubMed database up to November 2018.
- Inclusion of English literature articles using keywords: binarization, choroid/al, enhanced depth spectral domain/swept source optic coherence tomography.
- Analysis of 37 selected articles based on studied disease, binarization method, variables, and outcomes.
Main Results:
- Thirty-seven studies were analyzed, focusing primarily on retinal pathologies like age-related macular degeneration, central serous chorioretinopathy, and diabetic retinopathy.
- Binarization techniques were also applied to study choroidal characteristics in inflammatory diseases, corneal dystrophies, and post-surgical follow-up.
- The review discusses the benefits and limitations of various binarization methods.
Conclusions:
- Choroidal image binarization is a promising approach for detailed in vivo study of choroidal subcomponents.
- This technique facilitates a more granular understanding of choroidal structure in health and disease.
More Related Videos
Related Concept Videos
01:19Clinical Applications of Epidermal Stem Cells
3.3K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.3K
01:11Local Anesthetics: Clinical Application as Spinal Anesthesia
1.4K
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
1.4K
01:29Local Anesthetics: Clinical Application as Epidural Anesthesia
695
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
695
01:16Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
1.3K
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
One of the advantages of...
1.3K
01:12Statistical Software for Data Analysis and Clinical Trials
1.4K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.4K
01:30Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
1.9K
Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...
1.9K