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Milk vomiting or regurgitation in the first 3 months of life: Something old-something new
146 Whitburn Road, Cleadon, Tyne and Wear SR67QS, United Kingdom.
Insights
Infant reflux and mild pyloric stenosis (PS) may share a cause: acid-induced pyloric sphincter hypertrophy. Revisiting historical observations supports this, suggesting ultrasound assessment for infant reflux diagnosis.
Area of Science:
- Pediatric Gastroenterology
- Infant Physiology
- Surgical Pathology
Background:
- Reflux symptoms and self-cure timing in infants without sliding hernias mirror mild pyloric stenosis (PS).
- A shared etiology is proposed: temporary pyloric sphincter obstruction due to acid-induced hypertrophy.
Abstract:
The age of presentation of reflux symptoms and their self-cure in babies without a sliding hernia parallel those of mild pyloric stenosis of infancy (PS). It is proposed that this is because PS and, at least some cases of reflux, share the same cause-a temporary hold-up at the pyloric sphincter owing to acid provoked hypertrophy of the pyloric sphincter. In support of this theory, the written observations of John Thomson, Pediatrician from Edinburgh, in 1921 and Isabella Forshall, Pediatric Surgeon from Alder Hey Hospital, Liverpool, in 1958 are revisited. An analysis of both papers provides supportive evidence that, in at least some cases diagnosed as simple reflux, an underlying temporary hold up is present owing to early hypertrophy of the sphincter. It is recommended that sphincter thickness measurements should be made by ultrasonic assessment whenever uncomplicated reflux is diagnosed within the first 3 months of life.
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