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Obstructive Sleep Apnea in Patients With Primary-open Angle Glaucoma: No Role for a Screening Program
Dariusz Wozniak1,2, Rupert Bourne2,3,4, Gil Peretz4
1Respiratory Support and Sleep Centre.
Journal of Glaucoma
|June 5, 2019
Summary
Obstructive sleep apnea (OSA) is common in primary open-angle glaucoma (POAG) patients but not more prevalent than in controls. Screening for OSA in POAG patients is not supported by these findings.
Area of Science:
- Ophthalmology
- Sleep Medicine
- Public Health
Background:
- Obstructive sleep apnea (OSA) has been proposed as a potential contributing factor to primary open-angle glaucoma (POAG).
- This has led to discussions about screening POAG patients for OSA.
Purpose of the Study:
- To determine if OSA prevalence differs between POAG patients and non-glaucoma controls.
- To investigate associations between the apnea-hypopnea index (AHI) and glaucoma severity markers.
Main Methods:
- A single-center study involving 235 POAG patients and 160 controls.
- Comprehensive ocular assessments and nocturnal cardiorespiratory monitoring were conducted.
- Propensity score matching was used to compare OSA prevalence between groups.
Main Results:
- OSA prevalence was high in both POAG patients (58%) and controls (54%).
- No significant difference in OSA prevalence was found between matched POAG patients and controls.
- The AHI was not associated with visual field defects or retinal nerve fiber layer thinning.
Conclusions:
- A high prevalence of OSA exists in POAG patients, but it is comparable to the general population without glaucoma.
- The findings do not support routine screening for OSA in patients diagnosed with POAG.
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