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Updated: Jan 23, 2026
07:56
A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo
Published on: August 28, 2014
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Advances in Biomaterials and Technologies for Vascular Embolization
Jingjie Hu1, Hassan Albadawi1, Brian W Chong2
1Division of Vascular and Interventional Radiology, Minimally Invasive Therapeutics Laboratory, Mayo Clinic, 13400 East Shea Blvd., Scottsdale, AZ, 85259, USA.
Advanced Materials (Deerfield Beach, Fla.)
|June 7, 2019
Summary
Transcatheter embolization uses devices and materials to block blood vessels for treating vascular conditions. This review covers current and emerging embolic agents and technologies for interventional radiology.
Area of Science:
- Interventional Radiology
- Biomaterials Science
- Vascular Surgery
Background:
- Minimally invasive transcatheter embolization is a standard nonsurgical interventional radiology procedure.
- It involves the deliberate occlusion of blood vessels to treat diseased or injured vasculature.
- A diverse range of embolic agents are currently used in clinical practice.
Purpose of the Study:
- To offer a comprehensive overview of current and emerging endovascular embolization technologies.
- To discuss devices, materials, mechanisms, and design guidelines in embolization.
- To identify limitations and challenges in embolic materials to foster field advancement.
Main Methods:
- Literature review of current and preclinical embolic agents and technologies.
- Analysis of biomaterial advancements, including foams, polymers, and gelling solutions.
- Discussion of device types, material properties, and mechanism of action.
Main Results:
- Established embolic agents include metallic coils, microspheres, and liquids.
- Novel preclinical agents leverage advanced biomaterials like shape-memory foams and biodegradable polymers.
- Key areas for advancement include material properties, delivery systems, and long-term efficacy.
Conclusions:
- Significant progress has been made in embolic agent technology.
- Further research into novel biomaterials and optimized delivery systems is crucial.
- Addressing current limitations will drive innovation in endovascular embolization.
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