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Published on: July 11, 2025
[Urogenital tuberculosis in children]
A E Soloviev1,2, A N Mayorov1,2, E A Efimov1,2
1) FGBOU VO Ryazan State Medical University of the Ministry of Health of Russia, Ryazan, Russia.
Insights
Pediatric urogenital tuberculosis (TB) incidence decreased significantly between the 1990s and 2010s. Advanced diagnostics and treatments improved outcomes for children with this condition.
Area of Science:
- Pediatrics
- Infectious Diseases
- Urology
Background:
- Urogenital tuberculosis (TB) in children presents a complex clinical challenge.
- Understanding trends in pediatric urogenital TB is crucial for public health initiatives.
Purpose of the Study:
- To analyze the evolving clinical spectrum of pediatric urogenital tuberculosis.
- To compare disease presentation and outcomes between two distinct time periods (1993-1997 and 2013-2017).
Main Methods:
- Retrospective analysis of pediatric patients diagnosed with urogenital TB.
- Utilized conventional diagnostic methods (clinical, laboratory, imaging, tuberculin skin test, urine culture).
- Employed contemporary diagnostic tools including urine culture, Diaskintest, ultrasound, and instrumental methods.
Main Results:
- A 1.5-fold decrease in pediatric urogenital TB cases was observed in the later period (2013-2017) compared to the earlier period (1993-1997).
- The proportion of destructive forms of urogenital TB decreased by fourfold.
- Improved diagnostic accuracy and treatment efficacy were noted with modern approaches.
Conclusions:
- The incidence of pediatric urogenital TB has declined.
- Contemporary diagnostic modalities significantly enhance the detection of urogenital TB in children.
- Multidisciplinary collaboration and public health interventions are vital for managing and identifying pediatric urogenital TB.
Aim:
To analyze the clinical spectrum of urogenital tuberculosis (TB) in children from 1993-1997 to 2013-2017, who were treated at the FSCU "Kiritsy".
Materials And Methods:
Clinical forms of urogenital tuberculosis were diagnosed in 195 children (stage 1) and 158 children (stage 2). Conventional methods of TB diagnosis, including clinical, laboratory, imaging studies, tuberculin skin test and urine culture for BCG were used. In all cases, standard treatment for TB in combination with physiotherapy were performed.
Results:
When comparing the clinical spectrum of urogenital tuberculosis in children in 1993-1997 yy. (stage 1) and 2013 and 2017 yy. (stage 2), who were treated at the children's tuberculosis clinic "Kiritsy", the authors concluded that during the last 5 years the number of children with urogenital tuberculosis had decreased by 1.5 times (195 children in 1 stage, 158 in 2 stage) and proportion of children with a destructive form of urogenital tuberculosis decreased by 4 times (15 children in stage 1, 4 in stage 2). The contemporary diagnostic methods (urine culture, Diaskintest, ultrasound, instrumental methods) contributed to improved diagnosis of urogenital tuberculosis. Novel powerful antituberculous antibiotics allowed to significantly improve treatment outcomes.
Results:
1) The incidence of urogenital tuberculosis in children over the past 5 years has decreased by 1.5 times compared with 90th years of the the last century. 2) At the current stage, the use of urine culture, Diaskintest, ultrasound, x-ray and instrumental methods contributes to the diagnosis of urogenital tuberculosis in children. 3) Multidisciplinary team consisted of pediatricians, pediatric urologists, phthisiopediatric as well as sanitary and educational work in the foci of infection allow to identify the urogenital tuberculosis in children.
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