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08:48
Separation and Fractionation of Culture Filtrate Proteins (CFPs) from Mycobacterium tuberculosis
Published on: July 11, 2025
565
[Urogenital tuberculosis in children].
A E Soloviev1,2, A N Mayorov1,2, E A Efimov1,2
1) FGBOU VO Ryazan State Medical University of the Ministry of Health of Russia, Ryazan, Russia.
Urologiia (Moscow, Russia : 1999)
|June 12, 2019
Summary
Pediatric urogenital tuberculosis (TB) incidence decreased significantly between the 1990s and 2010s. Advanced diagnostics and treatments improved outcomes for children with this condition.
Area of Science:
- Pediatrics
- Infectious Diseases
- Urology
Background:
- Urogenital tuberculosis (TB) in children presents a complex clinical challenge.
- Understanding trends in pediatric urogenital TB is crucial for public health initiatives.
Purpose of the Study:
- To analyze the evolving clinical spectrum of pediatric urogenital tuberculosis.
- To compare disease presentation and outcomes between two distinct time periods (1993-1997 and 2013-2017).
Main Methods:
- Retrospective analysis of pediatric patients diagnosed with urogenital TB.
- Utilized conventional diagnostic methods (clinical, laboratory, imaging, tuberculin skin test, urine culture).
- Employed contemporary diagnostic tools including urine culture, Diaskintest, ultrasound, and instrumental methods.
Main Results:
- A 1.5-fold decrease in pediatric urogenital TB cases was observed in the later period (2013-2017) compared to the earlier period (1993-1997).
- The proportion of destructive forms of urogenital TB decreased by fourfold.
- Improved diagnostic accuracy and treatment efficacy were noted with modern approaches.
Conclusions:
- The incidence of pediatric urogenital TB has declined.
- Contemporary diagnostic modalities significantly enhance the detection of urogenital TB in children.
- Multidisciplinary collaboration and public health interventions are vital for managing and identifying pediatric urogenital TB.
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