Palladium-Catalyzed Cyclocarbonylation Approach to Thiadiazafluorenones: A Correction
Lucia Veltri1, Roberta Amuso1, Corrado Cuocci2
1Laboratory of Industrial and Synthetic Organic Chemistry (LISOC), Department of Chemistry and Chemical Technologies , University of Calabria , Via Pietro Bucci 12/C , 87036 Arcavacata di Rende (CS), Italy.
Abstract:
The palladium-catalyzed carbonylation of 2-(propynylthio)benzimidazoles bearing a terminal triple bond leads to 2-methyl-1-thia-4a,9-diazafluoren-4-ones instead of the previously reported 3-methyl isomers, as unequivocally established by XRD analysis of a representative product. A correction is therefore provided here in order to rectify the previous erroneous assignment of the position of the methyl group. Moreover, the process has been generalized to substrates bearing an internal triple bond, which lead to 3-alkyl-2-methyl-1-thia-4a,9-diazafluoren-4-ones, whose structure was confirmed by XRD analysis of two representative derivatives.
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