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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Sensory Functions of the Skin01:16

Sensory Functions of the Skin

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The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Accessory Structures of the Skin: Nails01:05

Accessory Structures of the Skin: Nails

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Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
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Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
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Updated: Jan 23, 2026

Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging
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Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging

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Skin Cancer: Precancers.

Paul Bruner1, Benjamin Bashline

  • 1Firelands Regional Medical Center Family Medicine Residency, 1111 Hayes Ave, Sandusky, OH 44870.

FP Essentials
|June 13, 2019
PubMed
Summary

Actinic keratoses (AKs) and atypical moles are precancerous skin lesions. Early detection via physical examination and dermatoscopy, followed by appropriate management, is crucial to prevent progression to skin cancer.

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Actinic keratoses (AKs) are common sun-induced skin lesions with a variable progression rate to squamous cell carcinoma (SCC).
  • Atypical moles (melanocytic nevi) signify an elevated melanoma risk, especially in specific patient groups.
  • Early identification of precancerous lesions is possible through physical examination, enhanced by dermatoscopy.

Purpose of the Study:

  • To review the characteristics, diagnostic methods, and management strategies for actinic keratoses and atypical moles.
  • To highlight potential complications and the importance of surveillance for these precancerous skin lesions.

Main Methods:

  • Literature review of actinic keratoses and atypical moles.
  • Analysis of diagnostic modalities including physical examination, dermatoscopy, and biopsy.

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  • Summary of current management options for AKs and dysplastic nevi.
  • Discussion of potential complications and surveillance protocols.

    • Main Results:

    • Actinic keratoses can be treated with surgical methods, topical chemotherapy, or photodynamic therapy.
    • Management of atypical moles varies based on atypia degree, ranging from observation to surgical excision.
    • Biopsy is essential for definitive diagnosis of suspicious lesions.
    • Complications include cosmetic issues, pain, itching, recurrence, and malignant transformation.

    Conclusions:

    • Prompt diagnosis and management of AKs and atypical moles are vital for preventing complications and potential progression to skin cancer.
    • Regular self-examination and professional follow-up are recommended for surveillance of precancerous lesions.