Related Experiment Video
Updated: Jan 23, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
Published on: October 31, 2025
[A review on the relationship between breast milk nutrients and brain development in preterm infants]
1Department of Pediatrics, West China Second University Hospital, Sichuan University/Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, China. tj1234753@sina.com.
Insights
Breast milk is crucial for preterm infant brain development. Key nutrients like oligosaccharides, polyunsaturated fatty acids, and lactoferrin support long-term cognitive outcomes from infancy through adulthood.
Area of Science:
- Neonatal Nutrition
- Neuroscience
- Developmental Pediatrics
Background:
- Breast milk is the optimal nutrition for preterm infants.
- The impact of breast milk on brain development is increasingly recognized.
- These effects can extend throughout an individual's lifespan.
Purpose of the Study:
- To review current research on breast milk nutrients and preterm infant brain development.
- To explain the function of specific nutrients in supporting neurodevelopment.
- To highlight the long-term cognitive benefits of breastfeeding for preterm infants.
Main Methods:
- Literature review of recent scientific studies.
- Analysis of the role of specific breast milk components.
- Synthesis of findings on neurodevelopmental and cognitive outcomes.
Main Results:
- Specific nutrients in breast milk, including oligosaccharides, polyunsaturated fatty acids, and lactoferrin, are vital for brain development.
- Breastfeeding's influence on neurodevelopment shows lasting effects.
- These effects are evident in cognitive functions across different life stages.
Conclusions:
- Breast milk nutrients are essential for optimal brain development in preterm infants.
- Early nutrition significantly influences long-term cognitive health.
- Further research into these nutrients can inform clinical practice and improve outcomes.
Abstract:
Breast milk is the preferred food for preterm infants. In recent years, the role of breast milk in the brain development of preterm infants has attracted more and more attention. Studies have shown that the effect of breastfeeding on neurodevelopment and long-term cognitive outcome of preterm infants may persist into childhood, adolescence, and even adulthood. The nutrients in breast milk, such as oligosaccharides, polyunsaturated fatty acids, and lactoferrin, play an important role in this process. This article reviews the latest research advances in the role of breast milk nutrients in the brain development of preterm infants and elaborates on the concept and function of each nutrient.
Related Concept Videos
Relationship Formation
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Absorption of Nutrients
Enterocytes, which are specialized polar epithelial cells, line the mucosa of the small intestinal walls. These cells...
Ending Relationships
Relationship Growth

