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Post-Stroke Depression.

Omer C Ibrahimagic1, Dzevdet Smajlovic1, Suljo Kunic2

  • 1Department of Neurology, University Cinical Centre Tuzla and University of Tuzla, Tuzla, Bosnia and Herzegovina.

Materia Socio-Medica
|June 20, 2019
PubMed
Summary
This summary is machine-generated.

Post-stroke depression is less common in the subacute phase. While women showed higher depression scores, gender and lesion location did not significantly impact depression after ischemic stroke.

Keywords:
CerebrumDepressionSexStroke

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Area of Science:

  • Neurology
  • Psychiatry
  • Clinical Research

Background:

  • Post-stroke depression is a prevalent complication that hinders recovery.
  • Understanding depression's prevalence and risk factors after ischemic stroke is crucial.

Purpose of the Study:

  • To investigate the incidence of depression within 48 hours and 15 days post-ischemic stroke.
  • To analyze the relationship between post-stroke depression, gender, and lesion location (hemisphere and circulation).

Main Methods:

  • A cohort of 40 patients (mean age 65.3 years, 50% female) with confirmed ischemic stroke.
  • Depression levels assessed using the self-estimated Zung's scale (score ≥ 50 indicating depression).
  • Lesion localization determined using established criteria; temporal analysis of depression at acute and subacute phases.

Main Results:

  • Depression prevalence decreased from the acute (47.5%) to the subacute (25%) phase (p<0.019).
  • Women exhibited higher mean depression scores in both acute (49.1) and subacute (45.25) phases compared to men (44.6 and 41.5, respectively), though not statistically significant.
  • No significant differences in depression levels were observed based on the location of the ischemic stroke.

Conclusions:

  • Post-stroke depression incidence significantly reduces from the acute to the subacute phase.
  • While women tend to have higher depression scores, gender is not a statistically significant factor.
  • The location of the ischemic lesion does not correlate with the presence or severity of post-stroke depression.