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Enteropathic AIDS in Uganda. An endoscopic, histological and microbiological study
N Sewankambo1, R D Mugerwa, R Goodgame
1Department of Medicine, Makerere University Medical School Kampala, Uganda.
AIDS (London, England)
|May 1, 1987
Summary
Enteropathic AIDS patients in Uganda experience common infections like candidiasis. However, coccidian enteritis, including cryptosporidiosis and isosporiasis, is more prevalent than in developed nations.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Immunology
Background:
- Acquired immunodeficiency syndrome (AIDS) can lead to enteropathic complications.
- Understanding the spectrum of gastrointestinal infections in AIDS patients in sub-Saharan Africa is crucial.
Purpose of the Study:
- To investigate the prevalence and types of upper gastrointestinal infections in Ugandan patients with enteropathic AIDS.
Main Methods:
- Twenty-three Ugandan patients with enteropathic AIDS underwent upper gastrointestinal endoscopy, colonoscopy, and biopsy.
- Stool parasitology and culture were also performed.
Main Results:
- Oral and/or oesophageal candidiasis was observed in 22 patients.
- Coccidian enteritis, specifically cryptosporidiosis (11 patients) and isosporiasis (3 patients), affected 61% of patients.
- One case of Mycobacterium avium mycobacteriosis was identified.
Conclusions:
- Enteropathic AIDS in Uganda presents with a similar range of infections as in developed countries.
- The incidence of cryptosporidiosis and isosporiasis is notably higher in this Ugandan cohort.
Keywords:
Acquired Immunodeficiency Syndrome--complicationsAfricaAfrica South Of The SaharaBiologyDeveloping CountriesDiarrheaDiseasesEastern AfricaEndoscopyEnglish Speaking AfricaExaminations And DiagnosesGastrointestinal EffectsHiv InfectionsPhysical Examinations And DiagnosesPhysiologyUgandaViral Diseases