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A Mouse Model for Laser-induced Choroidal Neovascularization
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Bilateral Choroidal Osteoma Complicated by Bilateral Choroidal Neovascularization
Ophthalmic Surgery, Lasers & Imaging Retina
|June 25, 2019
Summary
This case study details a rare instance of bilateral choroidal osteoma in a child, complicated by choroidal neovascularization (CNV) in both eyes. Treatment with aflibercept improved vision in the affected eye, while the other remained stable.
Area of Science:
- Ophthalmology
- Oncology
Background:
- Choroidal osteoma is a rare, benign bone tumor of the choroid, typically presenting unilaterally.
- Choroidal neovascularization (CNV) is a known complication, occurring in less than half of choroidal osteoma cases.
Observation:
- A 10-year-old female presented with bilateral choroidal osteoma, a highly unusual presentation.
- Multimodal imaging and ultrasonography confirmed the diagnosis.
- Best-corrected visual acuity (BCVA) was 20/63 in the right eye (OD) and 20/25 in the left eye (OS).
Findings:
- The patient exhibited exudative CNV in the OD and non-exudative CNV in the OS, confirmed by OCT angiography (OCTA).
- A single aflibercept injection in the OD led to improved BCVA (20/32 at 1 month, 20/25 at 3 months) with no recurrence.
- The OS showed stable BCVA and imaging, suggesting a quiescent CNV.
Implications:
- This case highlights the possibility of bilateral choroidal osteoma and CNV, even in pediatric patients.
- Intravitreal aflibercept can be effective in managing exudative CNV secondary to choroidal osteoma.
- The contralateral eye's quiescent CNV suggests potential for spontaneous resolution or a less aggressive form of the condition.
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