Related Experiment Video
Updated: Jan 23, 2026

A Rat Carotid Balloon Injury Model to Test Anti-vascular Remodeling Therapeutics
Published on: September 19, 2016
[Reconsideration of Carotid Web and the Therapeutic Strategy]
Ichiro Kawahara1, Takeshi Hiu, Tomonori Ono
1Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center.
Abstract:
The term "carotid web" was first used in 1973 and is considered a rare form of fibromuscular dysplasia(FMD). A carotid web was reported to produce thrombus formation and cause of ischemic events. However, it is rarely reported because of its low incidence. As for the diagnosis, noninvasive routine radiological modalities such as ultrasonography or magnetic resonance angiography may have very low sensitivity due to the subtle nature of the entity. Therefore, these types of lesions may be often underdiagnosed. We describe three cases that presented with minor and recurrent major ischemic strokes resistant to medical management. All 3 cases had a good course with no recurrence after carotid endarterectomy. On pathological examination, all specimens revealed mild atherosclerotic change, although FMD was known to be a non-inflammatory and non-atherosclerotic angiopathy. Early detection of a carotid web is highly important. Three-dimensional CT angiography(3D-CTA)maximum intensity projection(MIP)imaging seems to be a reliable noninvasive technique, although catheter angiography is considered as the gold standard. The cases with carotid web have characteristics such as more recurrent ischemic stroke and resistance to medical management. Surgical treatment should be considered if medical management in unsuccessful. Moreover, even if asymptomatic, it might also be considered for cases with a growing web or with blood stasis behind the web.
More Related Videos
06:53A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application
Published on: July 9, 2020
09:19High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies
Published on: January 4, 2015
Related Concept Videos
Therapeutic Index
Therapeutic Communication
Verbal communication depends on language or a prescribed way of using words so that people can share information effectively. The critical aspects of verbal...
Microorganisms in Medicine and Therapeutics
Cholinergic Antagonists: Therapeutic Uses
Respiratory Tract: Ipratropium, aclidinium, and tiotropium treat asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). They protect against bronchoconstriction caused by irritants like cigarette smoke, sulfur dioxide, and ozone. They also help reduce nasopharyngeal...
Persuasion Strategies
Adrenergic Agonists: Therapeutic Uses
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...