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Updated: Jan 23, 2026

Inducing Post-Traumatic Epilepsy in a Mouse Model of Repetitive Diffuse Traumatic Brain Injury
Published on: February 10, 2020
The Level of Neuregulin-1 after Traumatic Brain Injury and Formation of Post-Traumatic Epilepsy
L M Gazaryan1, N V Selyanina1, Yu V Karakulova1
1E. A. Vagner Perm State Medical University, Ministry of Health of the Russian Federation, Perm, Russia.
Abstract:
We evaluated the serum level of neuregulin-1 in humans with traumatic brain injury. The highest levels of neuregulin-1 were revealed in patients with developing post-traumatic epilepsy and the lowest concentrations of this peptide were found in healthy controls. The patients with traumatic brain injury not aggravated by the development of post-traumatic epilepsy had intermediate levels of neuregulin-1.
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