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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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[Multi-level analysis on factors affecting the adherence to early antithrombotic therapy among people with acute

X Bai1, Y P Song1, X R Lyu1

  • 1School of Public Health, Peking University, Beijing 100191, China.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|June 27, 2019
PubMed

Insights

Adherence to early antithrombotic therapy for acute ischemic stroke (AIS) patients is influenced by both patient factors like age and income, and hospital characteristics such as stroke unit availability and region. Hospital quality significantly impacts treatment adherence.

Area of Science:

  • Neurology
  • Public Health
  • Health Services Research

Background:

  • Early antithrombotic therapy is crucial for acute ischemic stroke (AIS) patients.
  • Understanding determinants of adherence is key to improving outcomes.

Purpose of the Study:

  • To identify patient and hospital-related factors influencing adherence to early antithrombotic therapy in AIS patients.
  • To analyze the impact of hospital quality on treatment adherence.

Main Methods:

  • Analysis of 16,910 AIS patients aged 50+ from the China National Stroke Registry II.
  • Utilized univariate analysis and a 2-level logistic regression model.
  • Collected patient demographics, medical history, and hospital characteristics.

Main Results:

  • 84.75% of patients received early antithrombotic therapy.
  • Patient factors: age, income, insurance, dyslipidemia, hypertension, NIHSS score.
  • Hospital factors: hospital level, region, academic status, stroke unit, bed percentage.

Conclusions:

  • Hospital quality is significantly associated with adherence to early antithrombotic therapy.
  • Older AIS patients and those with higher NIHSS scores require focused attention for improved adherence.

Keywords:
Acute ischemic strokeAntithrombotic therapyMultilevel model

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