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Updated: Jan 22, 2026

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Contrast-enhanced swallow study sensitivity for detecting esophagojejunostomy leakage.

U Clemente-Gutiérrez1, J G Rodríguez-Chong2, J Morales-Maza1

  • 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.

Revista De Gastroenterologia De Mexico (English)
|July 2, 2019
PubMed
Summary

The contrast-enhanced swallow study showed limited 66% sensitivity for detecting esophagojejunostomy leaks after total gastrectomy. High suspicion is needed for negative studies, suggesting a more comprehensive diagnostic approach for anastomotic leaks.

Keywords:
Anastomosis esofagoyeyunalAnastomotic leakContrast-enhanced swallow studyEsophagojejunostomyEstudio contrastadoFuga de anastomosisGastrectomía totalTotal gastrectomy

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Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Diagnostic Imaging

Background:

  • Esophagojejunostomy leaks occur in up to 12.3% of total gastrectomy cases for gastric cancer.
  • Standardized diagnostic procedures for anastomotic leaks are lacking.
  • Early detection of leaks is crucial for patient outcomes.

Purpose of the Study:

  • To determine the diagnostic sensitivity of contrast-enhanced swallow studies for detecting esophagojejunostomy leakage.
  • To evaluate the effectiveness of imaging in identifying post-gastrectomy complications.

Main Methods:

  • Retrospective analysis of patients undergoing total gastrectomy for gastric adenocarcinoma (2002-2017).
  • Identification of demographic, clinical, and radiologic factors related to anastomotic leaks.
  • Calculation of the sensitivity of contrast-enhanced swallow studies for leak detection.

Main Results:

  • 31.01% of 58 patients experienced anastomotic leaks.
  • The contrast-enhanced swallow study demonstrated a diagnostic sensitivity of 66% for detecting leaks.
  • Gastric adenocarcinoma was the indication for surgery in all cases.

Conclusions:

  • The contrast-enhanced swallow study has limited diagnostic efficiency (66% sensitivity) for esophagojejunostomy leaks.
  • High clinical suspicion is recommended for patients with initially negative studies.
  • A more extensive diagnostic approach may be necessary when leaks are suspected.