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Analysis of Human Natural Killer Cell Metabolism
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Natural Killer Cells and Thyroid Diseases.

Eun Kyung Lee1,2, John B Sunwoo3

  • 1Center for Thyroid Cancer, National Cancer Center, Goyang, Korea.

Endocrinology and Metabolism (Seoul, Korea)
|July 2, 2019
PubMed
Summary

Thyroid hormone disorders are common, and aging impacts both thyroid function and immunity. This review explores the link between natural killer (NK) cells and thyroid health.

Keywords:
AnaplasticImmunotherapyKiller cells, naturalProgrammed cell death 1Thyroid cancer, papillaryThyroiditis

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Area of Science:

  • Endocrinology
  • Immunology
  • Cell Biology

Background:

  • Thyroid hormone disorders are prevalent endocrine conditions.
  • Aging negatively impacts both the endocrine and immune systems.
  • A bidirectional relationship exists between the endocrine and immune systems.

Purpose of the Study:

  • To review the relationship between natural killer (NK) cells and thyroid function.
  • To explore the role of NK cells in thyroid disease.

Main Methods:

  • Literature review of existing research on NK cells and thyroid function.
  • Analysis of studies investigating the interaction between NK cells and the thyroid gland.

Main Results:

  • Emerging evidence suggests a significant interaction between NK cells and thyroid gland function.
  • NK cells may play a role in the development or progression of thyroid diseases.

Conclusions:

  • The interplay between NK cells and the thyroid gland warrants further investigation.
  • Understanding this relationship could offer new insights into endocrine and immune system interactions.