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Exploring the Relationship between Diarrhea and Fatigue that can occur during Cancer Treatment: Using Structural

Velda J Gonzalez1, Jason Beckstead2, Maureen Groer3

  • 1Postdoctoral Fellow, College of Nursing, University of South Florida, Tampa, FL, United States; UPR/MDACC Partnership for Excellence in Cancer Research U54 CA096297.

Puerto Rico Health Sciences Journal
|July 2, 2019
PubMed
Summary
This summary is machine-generated.

Diarrhea significantly contributes to cancer-related fatigue. Managing diarrhea symptoms may help reduce fatigue experienced by cancer patients during treatment.

Keywords:
Cancer Symptom ScaleCancer therapy–related symptomsDiarrheaFatigueStructural equational modeling

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Area of Science:

  • Oncology
  • Symptom Management
  • Cancer Patient Care

Background:

  • Cancer treatment often leads to multiple co-occurring symptoms.
  • Fatigue is a prevalent and debilitating symptom for cancer patients.
  • Diarrhea is a common side effect of various cancer therapies.

Purpose of the Study:

  • To investigate the relationship between diarrhea and fatigue in cancer patients.
  • To test a model of the cancer-related symptom experience.
  • To understand how diarrhea impacts fatigue during cancer treatment.

Main Methods:

  • Secondary data analysis of self-reports from 102 cancer patients.
  • Utilized structural equation modeling to analyze symptom relationships.
  • Assessed fatigue and diarrhea using the Cancer Symptom Scale.

Main Results:

  • The structural model demonstrated adequate fit.
  • Diarrhea explained 7% of the variance in fatigue.
  • A significant positive relationship was found between diarrhea and fatigue (coefficient=0.267, p<0.05).
  • Diarrhea showed the strongest effect on fatigue interference.

Conclusions:

  • Diarrhea is a significant contributing factor to cancer-related fatigue.
  • Targeting diarrhea interventions may help prevent or reduce fatigue.
  • Managing diarrhea is a potential strategy for improving cancer patient quality of life.