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Updated: Jan 22, 2026
08:24
Conventional and Threshold-Tracking Transcranial Magnetic Stimulation Tests for Single-handed Operation
Published on: August 16, 2021
6.5K
Mobile Application for Adaptive Threshold Hunting in Transcranial Magnetic Stimulation
Summary
A new Android application simplifies determining the motor threshold (MT) for transcranial magnetic stimulation (TMS). This validated tool precisely measures MTs, enhancing accessibility for researchers and clinicians.
Area of Science:
- Neuroscience
- Biomedical Engineering
Background:
- Transcranial magnetic stimulation (TMS) is increasingly used, with motor threshold (MT) determination crucial for measuring corticospinal excitability.
- Current methods for MT assessment often rely on system-integrated tools or separate software, posing space and accessibility challenges.
Purpose of the Study:
- To introduce and validate a free Android-based mobile application, "ATH-tool", for adaptive threshold hunting of the MT.
- To provide a simple, validated, and shareable tool for recording MTs.
Main Methods:
- Computational validation using known true threshold values.
- Comparison with the Motor Threshold Assessment Tool 2.0.
- Simulation of motor evoked potentials (MEPs) using previously published data from 15 healthy subjects.
Main Results:
- The ATH-tool demonstrated high precision in capturing true MT values (error ≤ 0.9%).
- Excellent agreement was observed between the ATH-tool and the Motor Threshold Assessment Tool 2.0 (ICC ≥ 0.971).
- No significant differences in MT determination were found between the methods (p ≥ 0.151).
Conclusions:
- The novel mobile application offers a precise and reliable method for MT determination.
- The ATH-tool enhances the ease of use and accessibility of MT measurements for TMS research and clinical practice.
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