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A technical comparison of thrombectomy vacuum aspiration systems
Kurt Yaeger1,2, Annabelle Iserson1, Paul Singh1,3
1Neurological Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Journal of Neurointerventional Surgery
|July 6, 2019
Summary
The Penumbra Jet Engine generated the highest aspiration pressures and tip forces in mechanical thrombectomy device testing. Larger catheter diameters also increased suction force, though clinical impact requires further study.
Area of Science:
- Neuroendovascular surgery
- Biomedical engineering
Background:
- Mechanical thrombectomy is crucial for emergent large vessel occlusion, with outcomes depending on rapid reperfusion.
- Advancements in device technology offer various commercial options for aspiration catheters and suction pump systems.
Purpose of the Study:
- To compare the aspiration forces and catheter tip detachment forces of different commercial vacuum pumps.
- To evaluate the mechanical performance of aspiration systems used in mechanical thrombectomy.
Main Methods:
- Tested commercial suction pumps (Penumbra Jet Engine, Penumbra Max, Stryker Medela AXS, Microvention Gomco, 60 cc syringe) using artificial thrombi.
- Measured aspiration pressure and catheter tip detachment force.
- Analyzed the correlation between catheter inner diameter and tip force using statistical analysis.
Main Results:
- The Penumbra Jet Engine system produced the highest aspiration pressures (28.8 inches Hg) and tip force (23.68 gf).
- A significant correlation (r=0.98) was found between larger catheter inner diameter and increased tip force.
- The largest-bore catheter used with the Jet Engine generated the highest tip force (32.12 gf).
Conclusions:
- The Penumbra Jet Engine significantly outperforms other tested pumps in generating vacuum pressures and tip forces.
- Larger inner diameter aspiration catheters enhance tip suction forces.
- Further clinical research is needed to determine if these mechanical advantages translate to improved patient outcomes.
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