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Updated: Jan 22, 2026

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies
Published on: November 27, 2013
Reversible rearrangement of magnetic nanoparticles in solution studied using time-resolved SAXS method
Lanqing Huang1, Jingeng Mai2, Qihui Zhu2
1Complex Systems Division, Beijing Computational Science Research Center, 8 E Xibeiwang Rd, Haidian, Beijing 100193, People's Republic of China.
Abstract:
Superparamagnetic nanoparticles have broad applications in biology and medicines. Quantitative measurements of magnetic beads in solution are essential in gaining comprehensive understanding of their dynamics and developing applications. Here, using synchrotron X-ray sources combined with well controlled magnetic fields, the results from small-angle X-ray scattering (SAXS) experiments on superparamagnetic particles in solution under the influence of external magnetic fields are reported. The particles mostly remain in monodispersed states and the linear aggregates tend to be aligned with the external magnetic field. After removing the magnetic fields, the superparamagnetic nanoparticles quickly recover to their original states indicating high reversibility of the rearrangement under the control of a magnetic field. The external magnetic field instrument composed of paired permanent magnets is integrated into the SAXS beamline at the Shanghai Synchrotron Radiation Facility providing a platform for studying time-resolved dynamics induced by magnetic fields.
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