Related Experiment Video
Updated: Jan 22, 2026
06:22
Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
Published on: November 29, 2024
1.3K
Perioperative takotsubo cardiomyopathy: Implications for anesthesiologist
Shvetank Agarwal1, Chinar Sanghvi1, Nadine Odo1
1Department of Anesthesiology and Perioperative Medicine, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Annals of Cardiac Anaesthesia
|July 6, 2019
Summary
Takotsubo cardiomyopathy (TCM) presents transient heart dysfunction mimicking heart attacks. This review synthesizes current literature on TCM, especially in perioperative settings, highlighting knowledge gaps for future research.
Area of Science:
- Cardiology
- Cardiovascular Medicine
Background:
- Takotsubo cardiomyopathy (TCM) involves temporary heart muscle weakening without blocked arteries, often triggered by stress.
- TCM symptoms overlap with acute myocardial infarction (heart attack), complicating diagnosis.
- Perioperative settings add complexity due to anesthesia and surgical hemodynamic changes.
Purpose of the Study:
- To review and synthesize recent literature on Takotsubo cardiomyopathy.
- To identify knowledge gaps in TCM's understanding, particularly in the perioperative context.
- To guide future research directions for Takotsubo cardiomyopathy.
Main Methods:
- This is a narrative review.
- Literature synthesis on Takotsubo cardiomyopathy.
- Identification of research gaps.
Main Results:
- Takotsubo cardiomyopathy (TCM) diagnosis is challenging due to symptom overlap with myocardial infarction.
- Distinguishing TCM from myocardial infarction requires awareness of advanced diagnostic tools.
- Significant gaps remain in understanding TCM's causes, characteristics, and management, especially during surgery.
Conclusions:
- Further research is crucial to elucidate Takotsubo cardiomyopathy's etiopathogenesis and optimize perioperative management.
- Enhanced diagnostic strategies are needed to differentiate TCM from myocardial infarction.
- A deeper understanding of TCM's natural history and treatment is essential.
Related Concept Videos
01:30Cardiomyopathy II: Dilated Cardiomyopathy
492
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
492
01:29Cardiomyopathy IV: Restrictive Cardiomyopathy
488
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
488
01:29Cardiomyopathy III: Hypertrophic Cardiomyopathy
433
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
433
01:25Cardiomyopathy I: Introduction and Classification
521
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
521
01:29Cardiomyopathy VI: Nursing Management
321
Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
321
01:29Cardiomyopathy V: Interprofessional Care
361
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
361