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Preservation of Fertility in Testis Cancer Management

Robert Craig Sineath1, Akanksha Mehta1

  • 1Department of Urology, Emory University School of Medicine, 1365 Clifton Road, Building B, Suite 1400, Atlanta, GA 30322, USA.

The Urologic Clinics of North America
|July 7, 2019
PubMed

Insights

Testicular cancer and its treatments can impact male fertility. Fertility preservation, primarily through sperm cryopreservation, is crucial and should be offered before treatment begins.

Area of Science:

  • Oncology
  • Reproductive Medicine
  • Men's Health

Background:

  • Testicular cancer and its treatments significantly affect male fertility.
  • Fertility preservation is a vital component of survivorship care for these patients.
  • Early intervention is key for successful fertility preservation.

Purpose of the Study:

  • To outline the impact of testicular cancer and its therapies on fertility.
  • To review established and experimental fertility preservation options.
  • To discuss barriers to accessing fertility preservation services.

Main Methods:

  • Literature review of testicular cancer treatments and their effects on male reproductive health.
  • Analysis of current fertility preservation techniques, including sperm cryopreservation.
  • Examination of challenges faced by patients in accessing fertility preservation.

Main Results:

  • Sperm cryopreservation is the only established method for male fertility preservation.
  • Fertility preservation methods for prepubertal boys remain experimental.
  • Physicians require comprehensive knowledge of available fertility preservation options.

Conclusions:

  • Fertility preservation counseling and options must be offered to all patients diagnosed with testicular cancer before treatment initiation.
  • Understanding the impact of cancer and therapy on fertility is essential for informed decision-making.
  • Addressing barriers to care is critical to ensure equitable access to fertility preservation for testicular cancer patients.
Keywords:
Fertility preservationLeydig cellMetachronous neoplasmsSertoli cellSynchronous neoplasmsTesticular neoplasmsTestis cancer

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