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Updated: Jan 22, 2026

08:12
Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
Published on: June 5, 2019
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One decade ago, one decade ahead in progressive supranuclear palsy
Maria Stamelou1,2,3, Nikolaos Giagkou1, Günter U Höglinger4,5
1Parkinson's disease and Movement Disorders Department, HYGEIA Hospital, Athens, Greece.
Summary
Progressive Supranuclear Palsy (PSP) understanding has revolutionized in the last decade. Future research aims to discover biomarkers and develop therapies for this rare neurological disorder.
Area of Science:
- Neuroscience
- Neurology
Background:
- Progressive Supranuclear Palsy (PSP) understanding has significantly advanced in the last decade.
- Historically, limited knowledge existed regarding PSP's clinical spectrum and pathophysiology.
Observation:
- The past decade has seen the discovery of PSP's wide clinical spectrum, leading to revised diagnostic criteria in 2017.
- Numerous large-scale, double-blind clinical trials for disease-modifying agents have provided novel insights into PSP biomarkers and progression.
Findings:
- Recent advancements have deepened the understanding of PSP's pathophysiological processes.
- These insights have facilitated the design and execution of clinical trials.
Implications:
- Future efforts will focus on biomarker discovery for earlier and more accurate PSP diagnosis.
- The ultimate goal is developing neuroprotective therapies for early-stage intervention in PSP patients.
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