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Updated: Jan 22, 2026

Primary Culture of Human Vestibular Schwannomas
10:50

Primary Culture of Human Vestibular Schwannomas

Published on: July 20, 2014

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Characteristics and Outcomes of Pediatric Vestibular Schwannomas

Tyler A Janz1,2, Philip Ryan Camilon3, Anthony Y Cheung3

  • 1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina.

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [And] European Academy of Otology and Neurotology
|July 11, 2019
PubMed

Insights

Pediatric vestibular schwannomas (VSs) are typically diagnosed in adolescence, with excellent survival rates approaching 97% for children. Treatment decisions for VSs depend on tumor size, offering valuable insights for patient counseling.

Area of Science:

  • Pediatric Oncology
  • Neurosurgery
  • Tumor Biology

Background:

  • Vestibular schwannomas (VSs) are rare tumors affecting the nerve connecting the ear to the brain.
  • Understanding the characteristics and outcomes of pediatric VSs is crucial for effective management.

Purpose of the Study:

  • To analyze the demographics, treatment approaches, and survival rates of children diagnosed with vestibular schwannomas.
  • To provide data that can aid healthcare providers in counseling pediatric patients and their families.

Main Methods:

  • Utilized the Surveillance, Epidemiology, and End Results (SEER) database for analysis.
  • Included pediatric patients (0-18 years) diagnosed with vestibular schwannoma between 2004 and 2014.
  • Classified cases based on ICD-O-3 codes for acoustic nerve tumors and specific histology types.

Main Results:

  • Identified 148 pediatric vestibular schwannoma cases, with a mean age at diagnosis of 13.9 years.
  • Tumor treatment varied, including surgery alone (55.4%), no treatment (30.4%), radiation alone (4.1%), and combined surgery and radiation (8.1%).
  • Median tumor size significantly differed across treatment groups, and the 5-year overall survival rate was 97%.

Conclusions:

  • Pediatric vestibular schwannomas predominantly affect adolescents, with no significant gender predilection.
  • Treatment strategies for pediatric VSs are influenced by tumor size.
  • Survival outcomes for children with vestibular schwannomas are highly favorable.
Abstract

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