Related Experiment Videos
Recurrent skin infections: a diagnostic enigma
R F Edlich1, J A Tafel, G T Rodeheaver
1Department of Plastic Surgery and Biomedical Engineering, University of Virginia School of Medicine, Charlottesville 22908.
Summary
Recurrent skin infections can be diagnosed with a comprehensive evaluation of the infected tissue and systemic factors. This approach identifies underlying causes, leading to effective treatment plans for chronic wound repair.
Area of Science:
- Dermatology
- Infectious Diseases
- Immunology
Background:
- Recurrent skin infections present a diagnostic challenge.
- Effective management requires identifying underlying causes impacting host defenses and wound repair.
Purpose of the Study:
- To present a rational diagnostic plan for recurrent skin infections based on 25 years of clinical experience.
- To outline a comprehensive approach for evaluating patients with persistent skin infections.
Main Methods:
- Detailed patient history and wound examination.
- Histologic and microbiologic examination of infected tissue.
- Systemic evaluation for immune deficiencies, metabolic/endocrinologic dysfunction, malnutrition, and collagen synthesis defects.
Main Results:
- A systematic diagnostic strategy can resolve the enigma of recurrent skin infections.
- Identifying systemic factors is crucial for successful treatment outcomes.
Conclusions:
- A comprehensive diagnostic plan integrating local tissue assessment with systemic evaluation is effective for managing recurrent skin infections.
- This approach aids in understanding and addressing factors that compromise host defenses and wound healing.