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Updated: Jan 22, 2026

Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug Delivery
Published on: June 23, 2020
A NIR light-triggered drug delivery system using core-shell gold nanostars-mesoporous silica nanoparticles based on
Andy Hernández-Montoto1, Mónica Gorbe2, Antoni Llopis-Lorente1
1Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico, Universitat Politècnica de València, Universitat de València, Spain. rmaez@qim.upv.es and CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain.
Abstract:
Gold nanostars coated with a mesoporous silica shell and functionalized with poly(ethylene glycol) containing photolabile 2-nitrobenzyl moieties are able to release doxorubicin after NIR light irradiation at low power irradiance via a multiphoton absorption photo-dissociation process.
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