Related Experiment Video
Updated: Jan 22, 2026

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
Published on: August 11, 2015
Successful Resolution of Prominent Somatic Delusions Following Bi-temporal Electroconvulsive Therapy in a patient
Joshua L Cohen1, My-Hanh Thi Vu1, Mirza Adam Beg1
1Cohen, PhD, School of Medicine, University of Alabama at Birmingham. Thi Vu, MD, PGY3 Resident, Department of Psychiatry, University of Alabama at Birmingham. Adam Beg, BS, School of Medicine, University of Alabama at Birmingham. Sivaraman, MD, Assistant Professor, Department of Psychiatry, University of Alabama at Birmingham. Birur, MD, Associate Professor, Department of Psychiatry, University of Alabama at Birmingham.
Abstract:
Somatic delusions occur in a variety of psychiatric disorders including schizophrenia, major depressive disorder, and bipolar disorder. Somatization is associated with lower quality of life and greater risk for suicide. Treatment of somatic delusions is extremely challenging. Here we report an interesting case of severe somatic delusions in a 48-year-old African-American female with a long history of treatment resistant schizoaffective disorder, with multiple somatic complaints surrounding constipation, pregnancy, jaw pain, body aches, vaginal itch, malodorous urine, and neck pain, despite normal clinical examinations and negative medical work up. Additionally, she endorsed persistent auditory and visual hallucinations. Her symptoms remained resistant to several trials of psychotropic medications, including clozapine. Chart review of past hospitalizations revealed significant improvement with Electroconvulsive Therapy (ECT), so the team decided to perform a course of six bi-temporal ECT treatments administered over two weeks. Stimulation was applied at a current of 800 mA for 4.5s, with a pulse width of 1 ms and frequency of 60 Hz. This case illustrates the successful use of ECT in treating prominent somatic delusions in a patient with treatment-resistant schizoaffective disorder.
Related Concept Videos
Electroconvulsive Therapy
Treatment Resistant Cancers
¹H NMR of Labile Protons: Temporal Resolution
The –OH proton in alcohols typically appears in the range of δ 2 to 5 ppm but can vary depending on the specific...
Treatment Strategies for Psychological Disorders
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Ecological Succession
¹H NMR of Conformationally Flexible Molecules: Temporal Resolution

