Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Relationship Formation02:12

Relationship Formation

45.2K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
45.2K
Ending Relationships01:28

Ending Relationships

174
The dissolution of intimate relationships presents complex emotional and psychological challenges, particularly when emotional bonds are strong, the relationship is long-standing, and perceived alternatives are limited. This distress often intensifies in romantic breakups, where the initiator may experience greater turmoil than the rejected partner. Contributing factors include residual attachment, guilt over causing pain, and uncertainty about how to manage the situation. The stress is further...
174
Relationship Growth01:27

Relationship Growth

209
Interpersonal relationships progress through stages, beginning with awareness and moving toward mutuality, where emotional connections deepen. While many relationships remain at moderate levels of mutuality, deeper connections form through self-disclosure, trust, and interdependence.Self-DisclosureSelf-disclosure involves revealing personal information, starting with surface-level details and gradually progressing to more intimate content. As trust grows, individuals feel more comfortable...
209
Phase Diagrams02:39

Phase Diagrams

49.0K
A phase diagram combines plots of pressure versus temperature for the liquid-gas, solid-liquid, and solid-gas phase-transition equilibria of a substance. These diagrams indicate the physical states that exist under specific conditions of pressure and temperature and also provide the pressure dependence of the phase-transition temperatures (melting points, sublimation points, boiling points). Regions or areas labeled solid, liquid, and gas represent single phases, while lines or curves represent...
49.0K
Social Relationships and Well-Being01:30

Social Relationships and Well-Being

268
The significance of social relationships in psychological well-being is a well-established area of inquiry within social psychology. Research consistently demonstrates that the presence of meaningful, supportive relationships enhances emotional health, while the absence or deterioration of such connections can contribute to psychological distress. Relationships serve as a foundation for emotional support, identity, and social belonging, all of which are critical to an individual’s overall...
268
Phase Transitions02:31

Phase Transitions

22.7K
Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to...
22.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

To the homeRNAmax: Developing an Improved Blood Self-Collection and Stabilization Platform for Remote Transcriptomic Studies.

Analytical chemistry·2026
Same author

Characterization of pre-analytical blood collection and stabilization parameters to maintain endogenous protein levels for remote blood sampling technology.

bioRxiv : the preprint server for biology·2026
Same author

Adaptation modulates effective connectivity and network stability.

Frontiers in computational neuroscience·2026
Same author

To the homeRNAmax: Developing an Improved Blood Self-Collection and Stabilization Platform for Remote Transcriptomic Studies.

bioRxiv : the preprint server for biology·2025
Same author

Towards optimizing target engagement in non-invasive trigeminal nerve stimulation: anatomical characterization of the human trigeminal nerve.

Journal of neural engineering·2025
Same author

Feasibility of implementing a non-invasive self-sampling method for saliva specimens that can be used for the diagnosis of respiratory infections among paediatric patients in the Tshwane District, South Africa: a study protocol.

BMJ open·2025

Related Experiment Video

Updated: Jan 22, 2026

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
07:52

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

806

Phase relationship between micro-electrocorticography and cortical neurons.

Thomas J Richner1, Sarah K Brodnick1, Sanitta Thongpang1

  • 1Biomedical Engineering, 1550 Engineering Drive, University of Wisconsin, Madison, WI, United States of America.

Journal of Neural Engineering
|July 19, 2019
PubMed
Summary
This summary is machine-generated.

Neurons preferentially fire at specific phases of electrocorticography (ECoG) signals, a relationship influenced by brain state and stimuli. This understanding is crucial for interpreting ECoG data and designing brain-computer interfaces.

More Related Videos

Juxtasomal Biocytin Labeling to Study the Structure-function Relationship of Individual Cortical Neurons
10:36

Juxtasomal Biocytin Labeling to Study the Structure-function Relationship of Individual Cortical Neurons

Published on: February 25, 2014

14.0K
Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs
08:30

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Published on: March 31, 2023

3.6K

Related Experiment Videos

Last Updated: Jan 22, 2026

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
07:52

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

806
Juxtasomal Biocytin Labeling to Study the Structure-function Relationship of Individual Cortical Neurons
10:36

Juxtasomal Biocytin Labeling to Study the Structure-function Relationship of Individual Cortical Neurons

Published on: February 25, 2014

14.0K
Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs
08:30

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Published on: March 31, 2023

3.6K

Area of Science:

  • Neuroscience
  • Electrophysiology
  • Signal Processing

Background:

  • Electrocorticography (ECoG) is vital for mapping epilepsy and developing brain-computer interfaces.
  • Understanding the link between surface potentials and neuronal firing is key for ECoG signal interpretation and electrode design.
  • Local field potentials (LFPs) are theorized to arise from synchronized synaptic potentials.

Purpose of the Study:

  • To investigate the spatiotemporal relationship between micro-ECoG signals and cortical neuronal firing patterns.
  • To test the hypothesis that cortical neurons fire at preferred, spatially dependent phases of the micro-ECoG signal.

Main Methods:

  • Custom fabrication of micro-ECoG electrode arrays for cortical insertion.
  • Simultaneous recording of micro-ECoG signals and intracortical LFPs/spikes.
  • Analysis of spectral coherence and spike-phase coupling under varying brain states and stimuli.

Main Results:

  • Spectral coherence between micro-ECoG and LFPs decreased with distance and frequency.
  • Neuronal spiking predominantly occurred at preferred phases and frequencies of the micro-ECoG signal.
  • Dexmedetomidine altered preferred spiking frequencies and shifted ECoG spectra to lower frequencies, enhancing spike-phase coupling; visual stimuli modulated gamma-frequency phase coupling.

Conclusions:

  • The phase relationship between cortical spikes and micro-ECoG signals is dynamic and influenced by brain state, location, cortical structure, and external stimuli.
  • Lower frequency shifts in ECoG signals indicate increased spike-phase coupling.
  • Neurons exhibit transient phase-locking to ECoG signals, particularly during sensory stimulation.