Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Purpose of Health Records I01:11

Purpose of Health Records I

1.7K
The vital purpose of health records is to provide a complete and accurate account of a patient's medical history, including communication, diagnostic and therapeutic orders, care planning, research, and quality review.
Here's a breakdown of how health records serve these purposes:
1.7K
Purpose of Health Records II01:19

Purpose of Health Records II

1.4K
Health records serve various essential purposes in the healthcare system. Here are some key purposes:
1.4K
In Vitro Drug Release Testing: Overview, Development and Validation01:10

In Vitro Drug Release Testing: Overview, Development and Validation

318
In vitro dissolution and drug release tests assess how quickly and how much of a drug is released from its dosage form into an aqueous medium under standardized laboratory conditions. These tests are essential tools in pharmaceutical development and quality assurance, offering insight into the drug's performance before clinical use.During formulation development, dissolution testing identifies incomplete or inconsistent drug release issues. It also supports decisions on selecting the optimal...
318
Reliability and Validity01:29

Reliability and Validity

13.8K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
13.8K
Data Reporting and Recording01:24

Data Reporting and Recording

5.4K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K
Electron Carriers01:24

Electron Carriers

91.5K
Electron carriers can be thought of as electron shuttles. These compounds can easily accept electrons (i.e., be reduced) or lose them (i.e., be oxidized). They play an essential role in energy production because cellular respiration is contingent on the flow of electrons.
Over the many stages of cellular respiration, glucose breaks down into carbon dioxide and water. Electron carriers pick up electrons lost by glucose in these reactions, temporarily storing and releasing them into the electron...
91.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

AHA/ACC/ESC/WHF Expert Consensus Document: Second Universal Definition of Heart Failure (2026).

European heart journal·2026
Same author

AHA/ACC/ESC/WHF Expert Consensus Document: Second Universal Definition of Heart Failure (2026).

Circulation·2026
Same author

AHA/ACC/ESC/WHF Expert Consensus Document: Second Universal Definition of Heart Failure (2026).

Journal of the American College of Cardiology·2026
Same author

The impact of post-acute sequelae of COVID-19 on cardiac function and structure: A systematic review and a hybrid individual participant data meta-analysis.

American journal of preventive cardiology·2026
Same author

Atrial Fibrillation Screening in Those with Rheumatic Heart Disease: A Narrative Policy Content Review.

Global heart·2026
Same author

Variations in the Risk of New-Onset Diabetes Following COVID-19 Infection Across Body Mass Index, Deprivation, Ethnicity and Geographic Regions: Population-Based Cohort Study in 42 Million People in England.

Diabetes, obesity & metabolism·2026
Same journal

Digital divide in clinical and operational artificial intelligence adoption and implementation stages: US hospital diffusion patterns and AI deserts.

Journal of the American Medical Informatics Association : JAMIA·2026
Same journal

Extending the fundamental theorem of biomedical informatics: a proposal and illustrative examples.

Journal of the American Medical Informatics Association : JAMIA·2026
Same journal

Human factors methods for designing safe health information technology: what do the experts think?

Journal of the American Medical Informatics Association : JAMIA·2026
Same journal

Equity-by-design for socially assistive robots as digital health tools.

Journal of the American Medical Informatics Association : JAMIA·2026
Same journal

Orchestrator multi-agent clinical decision support system for secondary headache diagnosis in primary care.

Journal of the American Medical Informatics Association : JAMIA·2026
Same journal

CUI-Curate: a GraphRAG-based framework for automated clinical concept curation for NLP applications.

Journal of the American Medical Informatics Association : JAMIA·2026
See all related articles

Related Experiment Video

Updated: Jan 21, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

7.5K

UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER.

Spiros Denaxas1,2,3,4,5, Arturo Gonzalez-Izquierdo1,2,4, Kenan Direk1,2,4

  • 1Institute of Health Informatics, University College London, London,United Kingdom.

Journal of the American Medical Informatics Association : JAMIA
|July 23, 2019
PubMed
Summary
This summary is machine-generated.

We developed a reproducible phenotyping framework using UK electronic health records (EHRs) for 51 conditions. This approach enhances data validity and sharing for translational research, supporting international health studies.

Keywords:
electronic health recordsmedical informaticspersonalized medicinephenotyping

More Related Videos

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
09:00

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

Published on: April 13, 2021

5.2K
Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
11:54

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

9.8K

Related Experiment Videos

Last Updated: Jan 21, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

7.5K
TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
09:00

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

Published on: April 13, 2021

5.2K
Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
11:54

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

9.8K

Area of Science:

  • Biomedical Informatics
  • Health Informatics
  • Translational Research

Background:

  • Electronic health records (EHRs) offer valuable disease data but are often unstructured and fragmented.
  • Existing EHR data requires significant curation for medical research due to varied coding systems and collection purposes.

Purpose of the Study:

  • To develop, validate, and share reproducible phenotypes from structured UK EHR data.
  • To create a framework applicable to translational research using national EHRs.

Main Methods:

  • Implemented a rule-based phenotyping framework with up to six validation approaches.
  • Applied the framework to 15 million individuals' primary care, hospitalization, and death records in England.
  • Utilized five controlled clinical terminologies including Read, ICD-9/10, OPCS-4, and DM+D codes.

Main Results:

  • Developed algorithms for 51 diseases, syndromes, biomarkers, and lifestyle risk factors.
  • Curated EHR phenotypes in the open-access CALIBER Portal.
  • Facilitated use by 40 research groups in 60 peer-reviewed publications.

Conclusions:

  • Described a UK EHR phenomics approach within the CALIBER platform.
  • Provided initial evidence of validity and utility for UK EHR data in health research.
  • Highlighted the importance of this approach for international EHR data utilization.