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Oral Rehydration in Children with Acute Diarrhoea and Moderate Dehydration-Effectiveness of an ORS Tolerance Test
Rhondi Kauna1, Kone Sobi1, Wendy Pameh2
1Department of Paediatrics, Port Moresby General Hospital, NCD, Papua New Guinea.
Insights
An oral rehydration solution (ORS) tolerance test helps identify children with moderate dehydration who can be successfully managed at home, reducing unnecessary hospitalizations and intravenous fluid use.
Area of Science:
- Pediatrics
- Gastroenterology
- Emergency Medicine
Background:
- Oral rehydration solution (ORS) is crucial for treating acute watery diarrhea but is underutilized, leading to unnecessary hospitalizations.
- Children with moderate dehydration often receive intravenous fluids instead of ORS, increasing healthcare costs and burden.
Purpose of the Study:
- To evaluate the effectiveness of an ORS tolerance test in emergency departments.
- To determine the ORS volume required for successful home management of children with moderate dehydration.
Main Methods:
- 129 children with moderate dehydration received ORS in a Children's Emergency Department (CED) for 2-4 hours.
- Discharge decisions were based on oral intake assessment and clinical judgment.
- Patients were followed up on days 2 and 5 to assess treatment outcomes.
Main Results:
- 61.2% (79/129) of children tolerated ORS well, drinking a median of 24.4 ml/kg.
- Of those who tolerated ORS, 79.7% (63/79) improved with home treatment.
- Children who failed home treatment had tolerated significantly less ORS (median 11.1 ml/kg) compared to those who succeeded (median 25.8 ml/kg).
Conclusions:
- An ORS tolerance test is a valuable tool for identifying children with moderate dehydration suitable for home-based oral rehydration therapy.
- Successful ORS tolerance in the emergency department predicts positive outcomes for home management.
- Implementing ORS tolerance testing can reduce hospital admissions and intravenous fluid administration for pediatric diarrhea.
Abstract:
Oral rehydration solution (ORS) is the mainstay of treatment of acute watery diarrhoea, but it is underutilized in many hospitals, resulting in children with moderate degrees of dehydration being unnecessarily hospitalized and receiving intravenous fluids. We aimed to assess the utility of an ORS tolerance test on initial presentation to an emergency department, and determine the volume of ORS a child with diarrhoea and moderate dehydration needed to tolerate to be successfully managed at home. One hundred and twenty-nine children with acute watery diarrhoea and moderate dehydration were given ORS and observed in a Children's Emergency Department (CED) over a period of 2-4 h. Patients were admitted, kept in the CED for further management or discharged, based on the assessment of oral intake and the clinical judgement of the treating health workers. Seventy-nine (61.2%) patients tolerated ORS well. They drank a median [interquartile range (IQR)] of 24.4 ml (IQR 12.5-28.8) ml/kg, were judged to have passed the ORS test and were discharged to continue oral rehydration treatment at home. At follow-up on days 2 and 5, 63/79 (79.7%) children had improved, were adequately hydrated and the diarrhoea had reduced. Sixteen of the 79 (20.3%) failed oral home treatment, with persisting diarrhoea, vomiting, hypokalaemia and/or weakness. The 63 who succeeded had tolerated a median of 25.8 (IQR 18.4-30.0) ml/kg of ORS in the CED, whilst the 16 who failed oral home treatment had tolerated 11.1 (IQR 9.1-23.0) ml/kg ORS (p < 0.001).
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