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Masticatory Dysfunction by Extensive Tooth Loss as a Risk Factor for Cognitive Deficit: A Systematic Review and
María Olimpia Paz Alvarenga1, Railson de Oliveira Ferreira1, Marcela Baraúna Magno2
1Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil.
Frontiers in Physiology
|July 24, 2019
Summary
Masticatory dysfunction (MD), or impaired chewing, is linked to a higher risk of cognitive deficit (CD). This meta-analysis found individuals with MD had a 46% greater chance of experiencing CD, though evidence certainty is low.
Area of Science:
- Neuroscience
- Gerontology
- Dental Medicine
Background:
- Cognitive decline is a normal part of aging, but can be worsened by risk factors.
- Masticatory dysfunction (MD) involves impaired chewing due to structural or functional issues, like tooth loss.
- MD can cause chronic stress, leading to changes in the hippocampus, crucial for memory.
Conclusions:
- Masticatory dysfunction is positively associated with an increased risk of cognitive deficit.
- The current evidence has low certainty, necessitating further research.
- Future studies should explore underlying factors of MD and use consistent measurements for robust risk estimation.
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