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A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Neonatal Mandibular Distraction Does Not Increase Inpatient Complications
Kevin C Lee1, Sidney B Eisig1, Sung-Kiang Chuang2,3,4
1Division of Oral and Maxillofacial Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.
Performing mandibular distraction osteogenesis (MDO) in newborns does not increase inpatient complications. Neonatal MDO is safe and should not be a contraindication for treatment at experienced centers.
Area of Science:
- Craniofacial Surgery
- Pediatric Surgery
- Health Services Research
Background:
- Mandibular distraction osteogenesis (MDO) is a surgical procedure to correct mandibular hypoplasia.
- The optimal timing for MDO, particularly during the neonatal period, requires further investigation regarding potential complications.
Purpose of the Study:
- To determine if performing MDO during the neonatal period increases inpatient complications.
- To assess the health-care burden associated with neonatal MDO compared to later intervention.
Main Methods:
- Retrospective cohort study utilizing the Kids' Inpatient Database (2000-2011).
- Included infants (<12 months) undergoing MDO, comparing neonatal (<28 days) vs. non-neonatal distraction.
- Analyzed outcomes: procedures, postoperative length of stay (pLOS), hospital charges, and transfer rates using regression models.
Main Results:
- Of 102 patients, 50 underwent neonatal MDO. Neonatal MDO patients had higher rates of cleft palate and feeding difficulties.
- Neonatal MDO was not associated with increased procedures, pLOS, hospital charges, or transfer rates.
- Secondary predictors, not neonatal age, influenced pLOS, hospital charges, and procedure counts.
Conclusions:
- Neonatal MDO is not linked to increased inpatient complications or health-care burden.
- Neonatal status should not be a contraindication for MDO at experienced surgical centers.
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