Characterization of Haemophilus influenzae isolated from patients with otitis media

Two hundred and twenty-three Haemophilus influenzae strains isolated from patients with otitis media throughout France were characterized by biotype, serotype, antibiotic susceptibility, type of beta-lactamase production and human erythrocyte agglutination properties. All strains fell in one of two groups. One group consisted of encapsulated type b strains, 50% of which were biotype I, often resistant to ampicillin (38.5% of beta-lactamase producing strains) and seldom positive for haemagglutination (3.8%). The second group was composed of non-encapsulated strains, 42% of which were of biotype II, 10.6% beta-lactamase producers and 10.5% positive for haemagglutination.