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Updated: Jan 21, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
05:51

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

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Factors Associated to Arterial Stiffness in Patients With Symptomatic Peripheral Artery Disease

Antonio Henrique Germano-Soares1, Breno Quintella Farah2, Aluísio Andrade-Lima3

  • 1Associated Graduate Program in Physical Education UPE/UFPB, University of Pernambuco, Recife, Pernambuco, Brazil.

Annals of Vascular Surgery
|July 29, 2019
PubMed

Insights

Aging, elevated body mass index, and higher blood pressure are linked to increased arterial stiffness in peripheral artery disease patients. This study identified key clinical factors associated with this condition.

Area of Science:

  • Cardiovascular Medicine
  • Vascular Biology
  • Clinical Research

Background:

  • Peripheral artery disease (PAD) significantly impacts cardiovascular health.
  • Arterial stiffness is a key indicator of vascular damage and cardiovascular risk.
  • Understanding factors influencing arterial stiffness in PAD is crucial for patient management.

Purpose of the Study:

  • To identify clinical factors associated with arterial stiffness in patients with symptomatic peripheral artery disease.
  • To investigate the relationship between various clinical characteristics and central arterial stiffness.

Main Methods:

  • Cross-sectional study including 181 patients with symptomatic PAD.
  • Central arterial stiffness assessed using carotid-femoral pulse wave velocity (cf-PWV).
  • Clinical data collected included sociodemographics, body mass index, comorbidities, and walking capacity.

Main Results:

  • Age, body mass index, and mean blood pressure were positively associated with cf-PWV.
  • Multiple linear regression identified these factors as significant predictors of arterial stiffness.
  • Statistical significance was observed for age (P=0.032), BMI (P=0.002), and mean blood pressure (P=0.021).

Conclusions:

  • Aging, elevated body mass index, and higher mean blood pressure are clinical factors associated with increased arterial stiffness in PAD patients.
  • These findings highlight modifiable and non-modifiable risk factors contributing to vascular damage in PAD.
  • Clinical attention to these factors may aid in managing arterial stiffness and cardiovascular risk in this population.
Abstract

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