Related Experiment Video
Updated: Jan 21, 2026
06:38
Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
Published on: October 13, 2018
16.3K
Pubertal orchestration of hormones and testis in primates
Indrashis Bhattacharya1,2, Souvik Sen Sharma2, Subeer S Majumdar2,3
1Department of Zoology & Biotechnology, HNB Garhwal University, Srinagar Campus, Srinagar, India.
Molecular Reproduction and Development
|August 2, 2019
Summary
Puberty reactivates the reproductive axis through hypothalamic neurons and pituitary hormones. This process matures testicular cells, enabling robust spermatogenesis and reproductive competence in adolescents.
Area of Science:
- Reproductive Endocrinology
- Developmental Biology
- Cell Biology
Background:
- Puberty, or adolescence, is a transitional phase marked by reproductive maturation.
- Spermatogenesis initiation is delayed in primates due to immature Sertoli cells, despite adequate gonadotropin levels.
Purpose of the Study:
- To review evolving concepts in pubertal regulation of hormone production.
- To elucidate the role of testicular cells in initiating robust spermatogenesis during puberty.
Main Methods:
- Literature review of recent studies on pubertal development and spermatogenesis.
- Analysis of hormonal regulation and cellular cooperation within the testes.
Main Results:
- Sertoli cells acquire functional competence for androgen and FSH receptors during the juvenile period.
- Reactivation of the hypothalamo-pituitary-testicular axis by Kisspeptin neurons triggers pubertal development.
- FSH and LH facilitate testicular cell maturation, leading to spermatogonial differentiation and spermatogenesis onset.
Conclusions:
- "Testicular puberty" is defined by the initiation of robust spermatogenesis.
- Pubertal hormone regulation and testicular cell cooperation are crucial for reproductive competence.
Related Concept Videos
02:13Types of Hormones
83.1K
Hormones can be classified into three main types based on their chemical structures: steroids, peptides, and amines. Their actions are mediated by the specific receptors they bind to on target cells.
83.1K
01:21Types of Hormones
6.6K
Hormones are classified into four main groups: steroids, eicosanoids, amino acid-based derivatives, and peptide hormones.
Steroids and eicosanoids fall under the category of lipid-soluble hormones. Steroids are derived from cholesterol and feature four interconnected carbon rings with variable side chains. Notable examples include estradiol from ovaries and testosterone from testes, exemplifying the critical roles of these lipid-soluble hormones in reproductive physiology. Eicosanoids, derived...
Steroids and eicosanoids fall under the category of lipid-soluble hormones. Steroids are derived from cholesterol and feature four interconnected carbon rings with variable side chains. Notable examples include estradiol from ovaries and testosterone from testes, exemplifying the critical roles of these lipid-soluble hormones in reproductive physiology. Eicosanoids, derived...
6.6K
01:33Hormonal Regulation
35.8K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
35.8K
01:40Hormonal Regulation
47.9K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
47.9K
01:56Plant Hormones
27.4K
Plant hormones—or phytohormones—are chemical molecules that modulate one or more physiological processes of a plant. In animals, hormones are often produced in specific glands and circulated via the circulatory system. However, plants lack hormone-producing glands.
27.4K
01:27Hormones of the Pituitary Gland
9.7K
The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
9.7K