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Evaluation of Risk Parameters in Bone Regeneration Using a Customized Titanium Mesh: Results of a Clinical Study
Amely Hartmann1, Helmut Hildebrandt2, Jörg U Schmohl3
1Oral Surgeon, Private Dental Practice, Filderstadt, Germany.
Implant Dentistry
|August 3, 2019
Summary
This study evaluated customized titanium mesh for bone regeneration, finding tobacco use and sinus lifts increase graft failure risk. However, the technique shows predictable outcomes for large jaw defects.
Area of Science:
- Oral surgery
- Regenerative medicine
- Biomaterials science
Background:
- Bone regeneration is crucial for dental implantology.
- Titanium mesh offers a scaffold for bone reconstruction.
- Platelet-rich fibrin enhances wound healing and bone formation.
Purpose of the Study:
- To evaluate risk factors associated with a novel bone regeneration technique.
- To assess the clinical outcomes of using customized titanium mesh for jaw defects.
- To identify factors influencing the success of bone grafting procedures.
Main Methods:
- Retrospective analysis of 70 grafting procedures in 65 patients.
- Utilized customized titanium mesh with Advanced- and Injectable-Platelet-Rich Fibrin (A- and I-PRF), membranes, and bone grafts.
- Classified mesh exposure and analyzed outcomes.
Main Results:
- Mesh exposure occurred in 37% of cases, significantly linked to graft material loss (P < 0.001).
- Tobacco abuse (P = 0.032) and simultaneous sinus floor elevation (P = 0.001) were identified as risk factors.
- Successful implant placement was achieved in most cases.
Conclusions:
- Customized titanium mesh is a viable protocol for treating large jaw defects.
- The technique demonstrates predictable outcomes, even with dehiscences.
- Risk factor identification aids in optimizing treatment planning for bone regeneration.
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