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Updated: Jan 20, 2026
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Sinus Floor Elevation and Antrostomy Healing: A Histomorphometric Clinical Study in Humans
Kazushige Tanaka1, Giovanna Iezzi2, Adriano Piattelli3
1Researcher, Department of Oral Implantology, Osaka Dental University, Osaka, Japan.
Implant Dentistry
|August 20, 2019
Summary
Histomorphometric analysis of maxillary sinus biopsies revealed greater mineralized bone and bone marrow at the alveolar crest compared to the antrostomy site following sinus-lift procedures.
Area of Science:
- Oral and Maxillofacial Surgery
- Regenerative Medicine
- Histology
Background:
- Sinus-lift procedures are crucial for maxillary augmentation.
- Understanding bone regeneration at different sinus sites is vital for successful outcomes.
Purpose of the Study:
- To compare histomorphometric bone regeneration.
- Evaluate biopsies from the antrostomy and alveolar crest.
- Assess outcomes after sinus-lift using porcine bone xenograft.
Main Methods:
- 12 volunteers underwent sinus floor elevation with collagenated corticocancellous porcine bone.
- Biopsies were collected from alveolar crest and antrostomy sites 9 months post-surgery.
- Histological analysis quantified mineralized bone, bone marrow, and xenograft percentages.
Main Results:
- Alveolar crest biopsies showed 40.1% mineralized bone and 40.1% bone marrow.
- Antrostomy biopsies revealed 26.0% mineralized bone and 23.4% bone marrow.
- Xenograft and soft tissue percentages varied between sites.
Conclusions:
- The alveolar crest site demonstrated significantly higher percentages of mineralized bone and bone marrow.
- These findings suggest preferential bone formation at the alveolar crest post-sinus-lift.
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