Indirect Sinus Augmentation With and Without the Addition of a Biomaterial: A Randomized Controlled Clinical Trial

Area of Science:

• Dentistry
• Oral Surgery
• Biomaterials Science

Background:

• Indirect sinus augmentation is a common procedure to increase bone height in the posterior maxilla for dental implant placement.
• The use of biomaterials in sinus augmentation aims to enhance bone regeneration and improve implant success rates.

Purpose of the Study:

• To compare the efficacy of indirect sinus augmentation with and without the addition of acemannan sponge graft.
• To evaluate the impact of acemannan on bone formation following sinus augmentation and simultaneous implant placement.

Main Methods:

• A randomized controlled clinical trial involving 30 patients aged 40-60 years.
• Patients underwent closed sinus lift, followed by randomization into blood clot control or acemannan sponge graft groups.
• Simultaneous implant placement and cone beam computed tomography (CBCT) for bone gain assessment at 3 and 6 months.

Main Results:

• The acemannan group showed significantly greater radiographic endo-sinus bone gain compared to the control group.
• Bone gain was approximately 2.4-fold at 3 months and 2-fold at 6 months in the acemannan group (P < 0.05).

Conclusions:

• Acemannan, as a biomaterial, significantly enhances bone formation in indirect sinus augmentation.
• The combination of acemannan, indirect sinus augmentation, and simultaneous implant placement improves bone regeneration outcomes.