Related Experiment Video
Updated: Jan 21, 2026

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches
Published on: October 8, 2021
Multifunctional Cosmetic Containing Blueberry and Tinosorb M®-Loaded Microparticles Improves Sunscreen Performance
Daiana Schiavon1, Daniela Novello Martini1, Gabriela Brocco1
1Curso de Farmácia, Universidade de Passo Fundo, Passo Fundo, Brasil.
This study shows blueberry extract and microparticles enhance sunscreen performance in multifunctional cosmetics. Blueberry microparticles improved photoprotection and added antioxidant benefits, increasing sunscreen effectiveness.
Area of Science:
- Cosmetic Science
- Photoprotection
- Material Science
Background:
- Multifunctional cosmetics require effective UV filters for sun protection.
- Incorporating natural ingredients like blueberry extract can offer additional benefits.
- Microparticle technology can improve the stability and performance of cosmetic formulations.
Purpose of the Study:
- To evaluate the impact of blueberry extract and microparticles (MP) on the sunscreen performance of multifunctional cosmetics.
- To determine optimal UV filter concentrations for high SPF and UVA-PF using in-silico modeling.
- To assess the physicochemical stability, in vitro SPF, and UV filter distribution in stratum corneum (SC) of the developed formulations.
Main Methods:
- UV filters (Octocrylene, Benzophenone-3, Tinosorb® M) were selected and concentrations optimized via in-silico modeling.
- Blueberry-loaded and Tinosorb® M-loaded microparticles (MP) were prepared using spray-drying.
- Cosmetic formulations were prepared with and without MPs, followed by characterization, stability testing, in vitro SPF, and tape stripping for SC distribution analysis.
Main Results:
- Formulations A and B (with MPs) exhibited superior rheological stability compared to formulation C (without MPs).
- In vitro SPF values were 51.0 (A), 33.7 (B), and 49.6 (C), with formulation A showing the highest efficacy.
- Blueberry extract demonstrated significant antioxidant capacity (16.71 μg/mL vitamin C equivalent).
Conclusions:
- Cosmetics incorporating microparticles demonstrated enhanced physical stability.
- Blueberry extract significantly boosted the photoprotective capacity and provided antioxidant/anti-aging benefits.
- The study validates the potential of blueberry extract and MP technology to improve sunscreen formulations.
Related Concept Videos
Impact Loading
In cases of elastic deformation,...
Eccentric Loading
Distributed Loads
For example, consider a bookshelf filled with books stacked vertically adjacent to each other. The weight of the books is evenly distributed over the length of the shelf. As a result, the pressure at different locations on the surface of the...
Stress: General Loading Conditions
The shearing force, possessing potential directionality within the plane of the section, is simplified into two component forces running parallel to the x and y axes....
General Case of Eccentric Axial Loading
Consider a member subjected to equal and opposite forces that are applied along a line that does not coincide with the member's neutral axis. In unsymmetrical...
Unsymmetric Loading of Thin-Walled Members
The concept of the shear center is crucial in countering the...

