Related Experiment Video
Updated: Jan 21, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Troponin release after exertional vasovagal syncope
Olivia Quinn1, David Jardine1, Christopher Florkowski2
1Department of General Medicine, Christchurch Hospital, Christchurch, New Zealand.
Abstract:
Troponin release following exertional vasovagal syncope has not previously been reported. A young man was investigated after being admitted twice with exertional syncope, each time followed by a 10-fold spike in troponin I over 24 h. Treadmill exercise tests reproduced his symptoms and demonstrated a vasovagal mechanism. During recovery, despite lying supine, he remained hypotensive for 5 min, with profound bradycardia and ST segment depression. We suspected that intense cardiovagal neural activity may have caused the troponin leak.
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