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Updated: Jan 21, 2026

In Vitro Thrombosis Test for Ventricular Assist Devices
Published on: March 21, 2025
Ventricular asystole in a CRT-D device. What is the mechanism?
Pavan Reddy1, Khuyen Do1, Rahul Doshi1
1Division of Cardiovascular Medicine, Department of Medicine, University of Southern California-Keck School of Medicine, Los Angeles, California.
Abstract:
We present a case of an 89-year-old man with a left ventricular assist device and cardiac resynchronization therapy device (CRT-D) who presented with multiple presyncopal events. On the night of admission, telemetry revealed a 13-s pause with appropriately timed pacing spikes but with failure to capture, followed by intermittent ventricular contraction with different QRS morphology. What was the mechanism for his ventricular asystole?
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