Related Experiment Video

Updated: Jan 21, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
08:51

A New Murine Model of Endovascular Aortic Aneurysm Repair

Published on: July 7, 2013

14.8K

Endovascular repair during complex thoracic aortic dissection using a micropore stent graft: Midterm follow-up

Zhe Wang1, Cheng Wang1, Fenghe Li1

  • 1Department of Vascular Surgery, First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|August 14, 2019
PubMed
Abstract

Insights

Micropore stent grafts (MSG) offer a safe and effective endovascular repair for thoracic aortic dissection (TAD), demonstrating excellent midterm outcomes. This approach promotes aortic remodeling and preserves vital organ branches with no major adverse events reported.

Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Vascular Biology

Background:

  • Thoracic aortic dissection (TAD) poses significant risks.
  • Endovascular repair aims to improve outcomes and minimize invasiveness.
  • Aortic remodeling and branch vessel preservation are key challenges in TAD treatment.

Purpose of the Study:

  • To evaluate the clinical efficacy and hemodynamic effects of micropore stent grafts (MSG) in patients with DeBakey types I and III TAD.
  • To assess the potential of MSG to promote aortic remodeling and preserve organ branches.

Main Methods:

  • Retrospective analysis of 26 patients with DeBakey types I and III TAD treated with MSG.
  • Follow-up included assessment of rupture, mortality, reintervention, branch patency, and hemodynamic effects at 12 months.

Main Results:

  • Zero rates for dissection rupture, conversion to open repair, and secondary reintervention at 12 months.
  • High rates of false lumen thrombosis (91.7% complete, 8.3% partial) and 100% branch vessel patency.
  • Post-operative reduction in aortic lumen pressure fluctuations and unstable blood flow.

Conclusions:

  • Endovascular treatment with MSG is a safe and effective option for DeBakey type I and III TAD.
  • MSG demonstrates good midterm outcomes, including aortic remodeling and branch vessel preservation.
  • Hemodynamic improvements suggest favorable aortic lumen conditions post-treatment.
Keywords:
endovascular repairhemodynamicsmicropore stent graftpatency ratethoracic aortic dissection

More Related Videos

Novel and Innovative Hybrid Technique for Type A Aortic Dissection06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

870
Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm04:56

Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm

Published on: August 1, 2025

490

Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
425
Nucleotide Excision Repair01:08

Nucleotide Excision Repair

Overview
40.6K
Mismatch Repair01:36

Mismatch Repair

Overview
43.5K
Thoracic Aorta01:15

Thoracic Aorta

The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
1.5K
Overview of DNA Repair02:25

Overview of DNA Repair

In order to be passed through generations, genomic DNA must be undamaged and error-free. However, every day, DNA in a cell undergoes several thousand to a million damaging events by natural causes and external factors. Ionizing radiation such as UV rays, free radicals produced during cellular respiration, and hydrolytic damage from metabolic reactions can alter the structure of DNA. Damages caused include single-base alteration, base dimerization, chain breaks, and cross-linkage.
Chemically...
33.5K
Base Excision Repair01:54

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
26.1K