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[Listeria monocytogenes kerato-uveitis]
A A Bialasiewicz1, L Holbach, H J Boltze
1Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg.
Klinische Monatsblatter Fur Augenheilkunde
|July 1, 1988
Summary
A severe Listeria monocytogenes eye infection in an elderly diabetic patient led to enucleation despite antibiotic treatment. This case highlights the aggressive nature of Listeria keratitis, even with appropriate therapy.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Corneal guttae and diabetes are predisposing factors for ocular infections.
- Listeria monocytogenes is a rare but serious cause of bacterial keratitis.
Observation:
- An 86-year-old patient with corneal gutae and diabetes developed a severe ulcerative keratitis.
- Microbial analysis identified Listeria monocytogenes serotype 4b as the causative agent.
Findings:
- Despite treatment with cephalosporins, amikacin, and gentamycin, the infection progressed.
- Ocular enucleation was necessary on day 16 due to massive fibrinous reaction and intractable pain.
Implications:
- This case underscores the potential for aggressive progression of Listeria keratitis, particularly in immunocompromised or elderly patients.
- Prompt diagnosis and aggressive management are crucial, though enucleation may still be required in severe cases.