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Updated: Jan 20, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
Interactive online consensus survival tool for esophageal squamous cell carcinoma prognosis analysis
Qiang Wang1, Fengling Wang1, Jiajia Lv1,2
1Department of Preventive Medicine, Institute of Biomedical Informatics, Bioinformatics Center, Cell Signal Transduction Laboratory, School of Software, School of Basic Medical Sciences, Henan University, Kaifeng, Henan 475004, P.R. China.
Abstract:
Esophageal squamous cell carcinoma (ESCC) is one of the most common types of cancer worldwide. However, operative diagnostic and prognostic systems for ESCC remain to be established. To improve assessment of the prognosis for patients with ESCC, the present study developed an online consensus survival tool for ESCC, termed OSescc. OSescc was built using 264 ESCC cases with gene expression data and relevant clinical information obtained from the Gene Expression Omnibus and The Cancer Genome Atlas databases. Kaplan-Meier survival plots with hazard ratios and P-values were generated by OSescc to predict the association between potential biomarkers and relapse free survival and overall survival. In addition, the current study integrated a function by which one could assess the prognosis based on an individual probe or the mean value of multiple probes for each gene, which helped improve the evaluation of the validity and reliability of the potential prognosis biomarkers. OSescc can be accessed at bioinfo.henu.edu.cn/DBList.jsp.
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