Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lipid packing contributes to the confinement of caveolae to the plasma membrane.

eLife·2026
Same author

Protein-enhanced small molecule disruptors of ordered membrane domains.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

The notochord: development, disease and stem cell-based modelling.

Development (Cambridge, England)·2026
Same author

Caveolae mechanics in cellular functions and disease.

Nature reviews. Molecular cell biology·2026
Same author

Mural cells protect the adult brain from hemorrhage but do not control the blood-brain barrier in developing zebrafish.

eLife·2026
Same author

Diffusing caveolin-1 scaffolds regulate mechanosignalling.

Nature cell biology·2026
Same journal

Syntaxin 12 Sustains Endosomal-Lysosomal Homeostasis and Survival in Glioblastoma Stem-Like Cells.

Traffic (Copenhagen, Denmark)·2026
Same journal

The Power of Nup85: Controlling Molecular Traffic and Cellular Fate.

Traffic (Copenhagen, Denmark)·2026
Same journal

Traffic Light Commentary-Src in the Upside Down: A Kinase Turned Inside Out.

Traffic (Copenhagen, Denmark)·2026
Same journal

Integrating Lateral Super-Resolution and Axial Progression Reveals Distinct Clathrin Pit Formation Pathways.

Traffic (Copenhagen, Denmark)·2026
Same journal

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies.

Traffic (Copenhagen, Denmark)·2026
Same journal

Mechanistic Insight Into Clathrin-Mediated Endocytosis in Plants.

Traffic (Copenhagen, Denmark)·2026
See all related articles

Related Experiment Video

Updated: Jan 20, 2026

Endothelial Cell Transcytosis Assay as an In Vitro Model to Evaluate Inner Blood-Retinal Barrier Permeability
10:56

Endothelial Cell Transcytosis Assay as an In Vitro Model to Evaluate Inner Blood-Retinal Barrier Permeability

Published on: June 7, 2022

6.0K

Caveolae: The FAQs.

Robert G Parton1,2, Miguel A Del Pozo3, Stéphane Vassilopoulos4

  • 1Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.

Traffic (Copenhagen, Denmark)
|August 27, 2019
PubMed
Summary
This summary is machine-generated.

Caveolae, abundant plasma membrane structures in vertebrate cells, remain enigmatic. This commentary addresses key questions about their formation and function, drawing from discussions at a 2019 workshop.

Keywords:
EHD2caveolaecaveolinscavinsendocytosislipodystrophymembranemuscular dystrophy

More Related Videos

Identification of Fatty Acids in Bacillus cereus
08:41

Identification of Fatty Acids in Bacillus cereus

Published on: December 5, 2016

10.1K
Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments
10:59

Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments

Published on: February 7, 2025

1.7K

Related Experiment Videos

Last Updated: Jan 20, 2026

Endothelial Cell Transcytosis Assay as an In Vitro Model to Evaluate Inner Blood-Retinal Barrier Permeability
10:56

Endothelial Cell Transcytosis Assay as an In Vitro Model to Evaluate Inner Blood-Retinal Barrier Permeability

Published on: June 7, 2022

6.0K
Identification of Fatty Acids in Bacillus cereus
08:41

Identification of Fatty Acids in Bacillus cereus

Published on: December 5, 2016

10.1K
Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments
10:59

Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments

Published on: February 7, 2025

1.7K

Area of Science:

  • Cell Biology
  • Membrane Biology
  • Biochemistry

Background:

  • Caveolae are flask-shaped invaginations of the plasma membrane found abundantly in vertebrate cells.
  • Despite their prevalence, the precise formation mechanisms and diverse functions of caveolae are not fully understood.

Purpose of the Study:

  • To address fundamental questions regarding the formation and function of caveolae.
  • To synthesize current knowledge and identify research gaps through expert discussion.

Main Methods:

  • The content is based on discussions from the first EMBO Workshop on Caveolae.
  • Expert round-table discussions synthesized existing data and proposed future research directions.

Main Results:

  • Key questions concerning caveolae biogenesis and cellular roles were discussed.
  • The commentary highlights areas of consensus and ongoing debate within the field.

Conclusions:

  • Further research is needed to elucidate the complex formation pathways of caveolae.
  • Understanding caveolae function is crucial for various cellular processes and potential therapeutic targets.