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Extreme dipping: More complex than it looks
Cesare Cuspidi1,2, Marijana Tadic3, Guido Grassi1
1Department of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.
Journal of Clinical Hypertension (Greenwich, Conn.)
|August 27, 2019
Summary
Extreme dipping (ED) blood pressure patterns are poorly understood and controversial. This pattern is a heterogeneous phenotype with varied night-time blood pressure, necessitating further detailed evaluation.
Area of Science:
- Cardiology
- Hypertension Research
- Clinical Physiology
Background:
- Clinical and prognostic implications of the extreme dipping (ED) blood pressure pattern remain poorly documented and debated.
- Existing research indicates significant variability in mean night-time blood pressure among individuals with the ED pattern, ranging from hypotension to hypertension.
Purpose of the Study:
- To highlight the heterogeneity of the extreme dipping phenotype.
- To emphasize the need for more detailed investigation into the clinical and prognostic significance of extreme dipping blood pressure patterns.
Main Methods:
- Review of existing literature on extreme dipping blood pressure patterns.
- Analysis of reported blood pressure variability in patients with extreme dipping.
Main Results:
- The extreme dipping blood pressure pattern is characterized by a wide spectrum of night-time blood pressure values.
- Significant inter-individual differences exist in mean night-time blood pressure within the extreme dipping phenotype.
Conclusions:
- The extreme dipping pattern represents a heterogeneous clinical phenotype.
- Further in-depth studies are required to fully understand the clinical and prognostic implications of extreme dipping blood pressure.
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