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Survey on Scientific Shared Resource Rigor and Reproducibility.

Kevin L Knudtson1, Robert H Carnahan2, Rebecca L Hegstad-Davies3

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Summary
This summary is machine-generated.

Shared scientific resources, known as core facilities, support reproducible research. A survey revealed cores routinely use best practices, despite unfamiliarity with NIH guidelines, to ensure research rigor and transparency.

Keywords:
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Area of Science:

  • Biomolecular research
  • Scientific core facilities
  • Research reproducibility

Background:

  • Shared scientific resources, or core facilities, are crucial for biomolecular research institutions.
  • The Association of Biomolecular Resource Facilities (ABRF) formed the Committee on Core Rigor and Reproducibility (CCoRRe) to enhance reproducible research.
  • CCoRRe aims to integrate advanced technologies, education, and communication in shared resource operations.

Purpose of the Study:

  • Assess the impact of U.S. National Institutes of Health (NIH) initiatives on scientific rigor and reproducibility on core facility services and technology development.
  • Identify challenges and opportunities in implementing new reporting requirements for rigorous research.
  • Determine new practices and resources needed to ensure research rigor.

Main Methods:

  • A survey was distributed to members of the Association of Biomolecular Resource Facilities (ABRF).
  • The survey solicited feedback on the influence of NIH initiatives on core services and technology.
  • The survey also aimed to identify challenges, opportunities, and resource needs for implementing rigorous research practices.

Main Results:

  • Many core facilities demonstrated unfamiliarity with current NIH guidelines on scientific rigor and reproducibility.
  • Challenges in implementing best practices for rigor and reproducibility were similar to those in providing support services.
  • Most cores already employ best practices, offering services like instrument access, training, and data management to support rigor and reproducibility.

Conclusions:

  • Feedback from the survey will inform the development of educational resources and best-practice guidelines by the ABRF.
  • These resources will support the core facility community and researchers in enhancing rigor and transparency.
  • The findings highlight the need for better dissemination and understanding of NIH initiatives within shared scientific resources.