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Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining
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The Cynomolgus Macaque MHC Polymorphism in Experimental Medicine

Takashi Shiina1, Antoine Blancher2,3

  • 1Department of Molecular Life Sciences, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.

Cells
|August 29, 2019
PubMed
Summary

Cynomolgus macaques, or Macaca fascicularis, are valuable models in research due to their MHC polymorphism, which impacts immune responses and disease susceptibility. Understanding this genetic variation is key for advancing experimental medicine.

Keywords:
MHC polymorphismMacaca fasciculariscynomolgus macaqueexperimental medicinenonhuman primate models

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