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Updated: Jan 20, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Cutaneous Adverse Reactions of Anticancer Agents
Subuhi Kaul1, Benjamin H Kaffenberger2, Jennifer N Choi3
1Department of Dermatology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
Abstract:
Cutaneous adverse effects are one of the most frequently observed adverse reactions with anticancer agents. This has only intensified with newer targeted and immunologic agents that present with a wide array of drug toxicities and skin reactions. The spectrum ranges from benign, localized dermatoses to generalized, life-threatening cutaneous toxicities. Herein, the authors review the cutaneous adverse effects observed with conventional chemotherapy as well as targeted agents, including the emerging immune checkpoint inhibitors, which have been revolutionary in the treatment of many malignancies.
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