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Updated: Jan 20, 2026
SI Units: 2019 Redefinition
Pathogen Reduction: The State of the Science in 2019
Eric A Gehrie1, Sara J Rutter2, Edward L Snyder2
1Department of Pathology, Division of Transfusion Medicine, The Johns Hopkins University School of Medicine, 1800 Orleans Street, Zayed Tower Suite 3081A, Baltimore, MD 21287, USA.
Abstract:
In the past 30 years, transfusion safety has increased substantially and blood transfusion is now a safer procedure than at any time in the past. Herein, we provide a comprehensive review of pathogen reduction, which is the new paradigm in transfusion safety. Specifically, we describe the various processes and technologies that are capable of diminishing or neutralizing infectious threats, including those that are not addressed or may not be detected by standard screening techniques. A special emphasis is placed on recent developments that are likely to impact patient care in 2019 and beyond.
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